Spec Technical Lab (Mass Spectrometry)- San Juan Capistrano, CA req64615 in San Juan Capistrano, CA at Quest Diagnostics

Date Posted: 11/3/2021

Job Snapshot

Job Description

Technical Lab Specialist (Mass Spectrometry)- San Juan Capistrano, California - Monday to Friday 

At Quest, Technical Lab Specialists (Mass Spectrometry) play an essential role in our success and in the services we provide. As a career, we offer a unique opportunity to develop your career with the #1 Diagnostic Lab in the US. We are tech driven, and we’re creating the lab of the future – an environment where you can deliver cutting edge diagnostics and help us drive new discoveries and breakthroughs.



The Technical Specialist has the overall responsibility for the planning, coordination, and evaluation of all technical and/or operational activities in the laboratory.  Responsible for performing duties so as to operate the lab with the highest quality safety and integrity, and in an efficient, economical and businesslike manner are of utmost importance. Duties will include but not be limited to, troubleshooting LCMS assays and instruments, optimizing conditions to improve performance of assays, and initiating and implementing cost reduction projects.  The incumbent actively supports and complies with all company and departmental policies and procedures.  This is a hands-on laboratory position.


  • Develop, plan and execute proactive approaches to optimize and modify existing tests and improve assay efficiencies.
  • Responsible for the research, evaluation, validation and implementation of new laboratory instruments and methodologies.
  • Troubleshooting and maintenance of mass spectrometry platforms and assays.
  • Contributes to SOP development of all documentation related to department needs.
  • Provide technical input to project teams and technical staff.
  • Actively supports and complies with laboratory policies and procedures.
  • Performs other job-related/miscellaneous duties as assigned by Scientific Management.
  • Adheres to all established laboratory safety requirements.  Required to use (a) personal protective equipment, including latex gloves (b) engineering controls and/or (c) work practice controls as directed by management.


  • BS or MS degree in analytical chemistry, biochemistry or related field with at least 3 years of direct mass spectrometry experience.
  • Significant experience in LC-MSMS in the analyses of peptides and proteins as well as small molecules from in vivo derived matrices is highly desirable.

Ability to compute basic statistical measures associated with quality control functions. Ability to work with mathematical concepts such as probability and statistical inference, linear algebra, and curve fitting at a sufficient level to assess the quality of departmental work.

Ability to define problems, collects data, establish facts, and draw valid conclusions.  Ability to analyze an extensive variety of business and technical information, make appropriate assumptions, and understand the implications of both the data limitations and assumptions on the conclusions drawn.