Senior NGS Scientist in San Juan Capistrano, CA at Quest Diagnostics

Date Posted: 2/15/2021

Job Snapshot

Job Description

Look for more than answers.


At Quest, we are on a continuous journey of discovery and development. It’s this attitude that has made us an industry leader and the #1 Diagnostic Lab in the US. For those joining us, we offer exciting and fast moving career opportunities where you can affect change at a rate unheard of in many organizations of our size and scope. While we invest in and develop technology to drive our innovations, our ongoing success relies on our people.

As a Senior NGS Scientist you will work for the world leader in the industry, with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge. You can make a real impact in a market that is growing and developing.

Senior NGS Scientist – the role

The Senior NGS Scientist will participate on the team of Advanced Diagnostics Core Lab scientists in the development and transfer of Next Generation DNA Sequencing (NGS) technology and core support automation to Lab Operations.  The Senior Scientist evaluates current and emerging technologies for potential use, and will be expected to work in the laboratory.

Job responsibilities:

  • Develop, plan, conduct and record results from complex experiments within a specific product or technology area.

  • Perform laboratory experiments following defined protocols and company procedures.

  • Report status of assigned projects through the preparation of detailed reports and documentation that summarize experiment results. Interpret results of experiments and recommends alternative experiments.

  • Prepare protocols, reports, work instructions (SOPs) and other written materials that meet Quality System Requirements.

  • Work within established parameters on individual assignments, on project teams for longer-term projects or as a leader for a project team or group. Present experimental results to supervisor or project team members and contribute ideas to improve team processes.

  • Participate in technical decisions affecting product development issues. Identify problems, investigate alternatives and recommend possible courses of action. Work with team members and other Business Unit personnel (operations, product transfer, project management, and quality departments) to meet department and project objectives.

  • Interact with cross-functional teams including: research and development, finance, business development, quality and regulatory departments.

  • May prepare and/or contribute to articles for publication. Present information at project meetings and may present findings at scientific meetings or to customers.

  • May attend technical conferences or seminars. Maintain knowledge of technological developments that may assist in the completion of an assignment or lead to new products, processes or procedures by reading current literature.

  • Effectively utilize and apply advanced methods or technologies. Contribute ideas for new product development typically within existing markets.

To qualify, the ideal candidate will have the following skills and experience:

  • Strong knowledge of various molecular technologies, such as, Next Generation Sequencing, RNA-Seq, RT-PCR, ddPCR, microarray, and other emerging technologies. 

  • Ability to perform due diligence of vendors, technologies and assays for ability to commercialize. 

  • Experience assessing novel strategies to optimize the NGS workflow.

  • Experience in laboratory automation workflow design and programming is strongly desired.

  • An advanced degree (M.A./Ph.D.) in Chemistry, Biochemistry or related scientific discipline.

  • Two to five (2-5) years of prior relevant experience often acquired in an academic or industrial environment with a Ph.D., at least 4 years of relevant experience with a Master's degree, or at least 6 years of relevant experience with a Bachelor's degree. GMP/QSR experience preferred.

Apply Today


Join us for competitive benefits and development opportunities in a progressive and supportive environment. Help us improve our service, and the experiences of our patients and colleagues. Work with us and together we can be better.

Your Quest career. Seek it out.





All requirements are subject to possible modifications to reasonably accommodate individuals with disabilities. Quest Diagnostics is an Equal Opportunity Employer: Women / Minorities / Veterans / Disabled / Sexual Orientation / Gender Identity or Citizenship. 

If you’re interested in career opportunities, but not ready to apply, join our talent network to stay connected to us and receive updates on the latest job opportunities and company news.

Group of people